PRP Facial in Jericho, NY

What Is SkinPen Microneedling?

The SkinPen is an FDA-cleared, medical-grade microneedling device renowned for its precision, safety, and consistent clinical results. Using a matrix of ultra-fine needles, the SkinPen creates controlled micro-channels in the skin’s surface — triggering the body’s natural wound-healing cascade and stimulating the production of new collagen and elastin in the treated area. These micro-channels also serve a critical secondary purpose: they allow the topically applied PRP or PRF to penetrate deeply into the skin rather than sitting on the surface — dramatically enhancing the absorption, effectiveness, and regenerative impact of the growth factors being delivered.

The result of combining SkinPen microneedling with PRP or PRF is a significantly more powerful skin renewal response than either treatment alone can produce — making PRP/PRF facial treatments at Bespoke Medesthetics one of the most effective regenerative skin rejuvenation options available without surgery or synthetic injectables.

PRP vs. PRF: What’s the Difference?

Both PRP and PRF are derived from a small sample of your own blood, which is processed in a centrifuge to concentrate the most beneficial regenerative components. Both are 100% natural and biocompatible — with no risk of allergic reaction. However, PRF represents a meaningful advancement over traditional PRP in several important ways.

PRP (Platelet-Rich Plasma)

PRP uses a higher-speed centrifugation process to isolate the platelet-rich plasma layer from the blood. The resulting product contains a concentrated supply of platelets and growth factors that stimulate cell turnover, accelerate tissue repair, and boost collagen production. PRP delivers excellent skin rejuvenation results, and many patients notice faster initial improvements due to the immediate release of growth factors upon application.

PRF (Platelet-Rich Fibrin)

PRF is processed using a lower centrifuge speed and without anticoagulants, producing a purer, more bioactive product that contains not only platelets and growth factors, but also white blood cells, stem cells, and a fibrin matrix. The fibrin scaffold acts as a natural slow-release delivery system — holding growth factors in the treatment area and releasing them gradually over time rather than all at once. This provides a sustained regenerative response that produces longer-lasting, more progressive results than standard PRP. PRF also contains white blood cells, which enhance the tissue repair environment and reduce inflammation more effectively. For these reasons, PRF is considered the next generation of regenerative facial therapy and is often the preferred option at Bespoke Medesthetics for patients seeking the most advanced, longest-lasting skin rejuvenation results.

For patients interested in the most advanced form of PRF therapy, we also offer EZ PRF Gel Injectable — which takes PRF technology a step further by combining it with an albumin matrix for both volumizing and regenerative effects, and our dedicated under eye PRP & PRF treatment program for targeted under-eye rejuvenation.

PRP & PRF With SkinPen Microneedling: How They Work Together

The combination of SkinPen microneedling with PRP or PRF creates a powerful, synergistic skin renewal effect that addresses multiple dimensions of skin aging simultaneously:

• The SkinPen creates thousands of micro-channels in the skin, triggering a collagen and elastin production response while also opening precise pathways for maximum growth factor absorption
• PRP or PRF is applied immediately following needling, allowing the concentrated growth factors to penetrate deeply through the micro-channels directly to the dermal layer where collagen synthesis occurs
• The growth factors then activate fibroblasts — the cells responsible for collagen and elastin production — accelerating and amplifying the skin’s natural regenerative response
• The fibrin matrix in PRF continues to release growth factors gradually over days to weeks following treatment, providing a sustained healing and remodeling effect that extends well beyond the initial session

The result is visibly smoother, firmer, more even, and more radiant skin that continues to improve progressively over the weeks and months following treatment — driven entirely by your own body’s biology.

Microneedling With PRP, PRF & Exosomes

For patients seeking the most advanced level of skin regeneration available, we offer microneedling combined with exosomes at Bespoke Medesthetics in Jericho, NY. Exosomes are nano-sized cellular messengers — derived from stem cells — that carry growth factors, proteins, lipids, and genetic signals that direct cellular repair and regeneration processes. When applied following microneedling, exosomes amplify the regenerative effect of PRP or PRF by enhancing skin repair, improving hydration and elasticity, and accelerating the production of new collagen and healthy skin cells. This triple combination delivers optimal rejuvenation results for all skin types and is particularly beneficial for patients dealing with advanced signs of aging, significant acne scarring, or skin that has been slow to respond to other treatments.

Benefits of PRP & PRF Facials at Bespoke Medesthetics

PRP and PRF facials with SkinPen microneedling at Bespoke Medesthetics in Jericho, NY deliver a wide range of skin rejuvenation benefits, including:

• Stimulated collagen and elastin production for firmer, more youthful skin
• Reduction in fine lines, wrinkles, and surface skin aging
• Improved acne scarring and post-inflammatory pigmentation
• More even skin tone and improved overall skin texture
• Enhanced skin hydration and plumpness at the cellular level
• Diminished dark circles, puffiness, and fine lines in the delicate under-eye area
• A naturally refreshed, radiant, and healthy-looking complexion
• 100% natural treatment — no synthetic materials, no foreign substances, virtually no allergy risk
• Minimal downtime compared to more aggressive resurfacing treatments

PRP and PRF facials pair beautifully with other regenerative and skin care treatments at Bespoke Medesthetics, including chemical peels, HydraFacial, and Morpheus8 RF microneedling. All new patients receive a complimentary skin analysis using our Alma IQ technology to guide their personalized treatment plan.

PRP & PRF Facial in Jericho, NY — Frequently Asked Questions